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MSK Announces 10 Clinical Trials for Mesothelioma

Memorial Sloan Kettering Cancer Center (MSK) has announced that it is now recruiting patients for at least 10 mesothelioma clinical trials. The Center says it is constantly testing new ways to fight mesothelioma and is often “the first” to be aware of the latest scientific discoveries and medical advances for the disease. MSK patients often “have access to clinical trials of new treatment options that are not available in most other hospitals.” The latest mesothelioma clinical trials at MSK include:

  • A Phase I Study of Immunotherapy with Emactuzumab and RO7009789 in Patients with Advanced Solid Tumors
  • A Phase I Study of LY3023414 in Patients with Advanced Cancer
  • A Phase I Study of Immunotherapy with Genetically Engineered T Cells (CAR T Cells) to Treat Mesothelioma and Malignant Pleural Disease from Lung and Breast Cancers
  • Phase I Study of PF-02341066 in People with Advanced Cancer
  • A Study of Pevonedistat Alone and in Combination with Chemotherapy in Patients with Mesothelioma
  • A Study of Stereotactic Body Radiation Therapy and Avelumab Immunotherapy to Treat Malignant Mesothelioma
  • A Phase II Study of BIBF 1120 (Nintedanib) for Recurrent Malignant Pleural Mesothelioma
  • A Phase II Study of Nintedanib plus Prednisone to Treat Radiation Pneumonitis
  • A Phase II/III Study of Chemotherapy with or without ADI-PEG 20 in Patients with Malignant Pleural Mesothelioma
  • A Phase III Study of Immunotherapy versus Chemotherapy to Treat Inoperable Pleural Mesothelioma

Per MSK, “these research studies evaluate the safety and effectiveness of new ways to diagnose and treat mesothelioma.” They can also give treatment teams information about your current plan of care. “Promising approaches that we’ve looked at so far include tumor vaccines, antibody therapies, T cell–based treatments, molecularly targeted medications, and the use of anticancer viruses.”

Because mesothelioma is often diagnosed in its later stages, treatment options are usually limited and the prognosis is often poor. However, MSK says that regardless of the stage of your disease, as a MSK patient, there will likely be a clinical trial option for you. This is often the case at most major cancer treatment centers around the world. At any given time, these facilities may have hundreds of clinical trials underway for most cancer diagnoses and stages of disease.

In the U.S., MD Anderson Cancer Center, Mayo Clinic, University of Chicago Medicine Comprehensive Cancer Center, Northwestern Medicine, and UH Seidman Cancer Center are just a few options.

If you have been diagnosed with mesothelioma, talk to your doctor about participating in a clinical trial. New and developing drugs have the potential to extend or save lives. Talk to your doctor today.

 

Sources 

"Mesothelioma Clinical Trials & Research." MSKCC.org. Memorial Sloan Kettering Cancer Center (MSK), 2018. Web. 26 Mar. 2018.